Hematopoietic progenitor cells of placental and umbilical cord blood: immunophenotypic analysis and differentiation potential in vitro

Kuchma M, Shablii V, Kyryk V., Svitina G.,  Shablii Yu., Lukash L., Lobintseva G.

Biotechnologia Acta. 2014;7(4):61–70 (In Ukraine)

A

B

C

D

Majority of hematopoietic progenitor cells both in full-term placenta (A) and umbilical cord blood (B) remains uncommitted, however, in placental tissue we found more amount of differentiated cells that include myeloid, later myeloid, erythroid, B-lymphoid, T-lymphoid and Natural Killer Cells-progenitors, also T-lymphocytes at the different stages of maturation. Placental hematopoietic progenitor cells (C) have similar potential for differentiation in vitro in comparison with cord blood ones (D).